Psoriasis

Psoriasis is a chronic autoimmune disease that affects the skin, causing rapid skin cell turnover. Normally, skin cells grow and shed in a regular cycle over a few weeks, but in people with psoriasis, this cycle is much faster. As a result, skin cells build up on the surface of the skin, creating thick, scaly patches that can be red, inflamed, and sometimes painful.

What happens inside the body?

In a person with psoriasis, the immune system mistakenly attacks healthy skin cells. This leads to an overproduction of skin cells and inflammation. T-cells, a type of white blood cell, become overly active and trigger the skin cells to divide too quickly. Instead of taking about 28-30 days to regenerate, the process only takes about 3-4 days, resulting in a buildup of skin cells on the surface that don’t have time to shed properly.

Symptoms of Psoriasis:

  1. Plaques: Red or pink patches of skin covered with silvery scales.
  2. Itching or Burning: The affected areas can be itchy, painful, or even cracked and bleeding.
  3. Dry Skin: Flaky skin, especially on areas where the patches are.
  4. Nail Changes: Dents or pits in the nails, and sometimes discoloration.
  5. Swollen Joints: In some cases, psoriasis can lead to a form of arthritis called psoriatic arthritis.
  6. Flare-Ups & Remission: Psoriasis can get worse (flare-ups) and improve (remission) periodically, often triggered by stress, weather, infections, or medications.

Types of Psoriasis:

  1. Plaque Psoriasis (the most common): Characterized by raised, red patches with silvery-white scales.
  2. Guttate Psoriasis: Small, drop-shaped spots appear, usually after a throat infection.
  3. Inverse Psoriasis: Red, shiny lesions that appear in skin folds like under the armpits, groin, or behind the knees.
  4. Pustular Psoriasis: Characterized by white pustules surrounded by red skin.
  5. Erythrodermic Psoriasis: A rare but severe form that causes widespread redness and shedding of the skin.
  6. Psoriatic Arthritis: Involves both the skin and joints, causing pain, stiffness, and swelling.

Causes & Triggers:

Psoriasis is genetic, meaning it tends to run in families. However, environmental triggers can cause it to appear or worsen. These include:

  • Stress: Emotional stress is one of the most common triggers.
  • Infections: Throat infections or skin infections can trigger or worsen psoriasis.
  • Weather: Cold, dry weather can lead to flare-ups, while sunlight can sometimes improve symptoms.
  • Medications: Certain drugs (like beta-blockers, lithium, or antimalarials) can cause flare-ups.
  • Skin Injury: Cuts, sunburns, or other skin trauma can trigger a flare (called the Koebner phenomenon).
  • Diet: Some foods might trigger flare-ups for some people (like alcohol or spicy foods).

Is Psoriasis Contagious?

No, psoriasis is not contagious. You cannot “catch” it from someone else.

Managing Psoriasis:

While there’s no cure for psoriasis, various treatments can help manage symptoms and control flare-ups:

  1. Topical Treatments:
    • Corticosteroids: Anti-inflammatory creams to reduce redness and scaling.
    • Vitamin D analogs: Help slow skin cell turnover.
    • Coal Tar: Reduces scaling and itching.
    • Topical Retinoids: Vitamin A derivatives that help normalize skin cell growth.
  2. Phototherapy:
    • Ultraviolet (UV) light treatment can slow skin cell turnover and reduce inflammation.
  3. Systemic Treatments (for moderate to severe cases):
    • Biologic drugs: Target specific parts of the immune system to reduce inflammation and skin cell turnover (e.g., TNF inhibitors, IL-17 inhibitors).
    • Oral medications: Drugs like methotrexate or acitretin that suppress the immune system or slow skin cell growth.
  4. Lifestyle Changes:
    • Stress management: Techniques like meditation, yoga, or therapy can help reduce stress.
    • Skin care: Moisturizing regularly to prevent dryness, using gentle skin care products, and avoiding hot water or harsh soaps.
    • Diet: Maintaining a healthy diet can help reduce inflammation and support immune function.

Impact on Life:

Psoriasis is more than just a skin condition; it can have a significant impact on a person’s quality of life. It can affect self-esteem and social interactions, as people might feel self-conscious about their appearance. Moreover, living with psoriasis increases the risk for other health problems, such as cardiovascular disease, diabetes, and depression.

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