Lichen Planus

🍃 Oral Lichen Planus

Lichen planus is a chronic inflammatory condition that can affect the skin, nails, and mucous membranes, including the oral mucosa (mouth). When it affects the mouth, it’s called oral lichen planus (OLP).


🧬 Cause:

  • Exact cause unknown
  • Considered an immune-mediated disorder where the body’s immune system attacks cells of the oral mucosa
  • May be triggered or worsened by:
    • Stress
    • Certain medications
    • Dental materials (e.g., amalgam)
    • Infections (like hepatitis C)

🩺 Clinical Features:

  • Typically affects middle-aged adults, more common in women
  • Appears as white, lacy patches (Wickham’s striae) on the inside of cheeks, tongue, or gums
  • Can also cause red, swollen, or ulcerated areas
  • Symptoms vary:
    • Some patients are asymptomatic
    • Others have burning sensation, pain, or sensitivity to spicy/acidic foods
  • May cause gum inflammation and soreness (desquamative gingivitis)

🔍 Diagnosis:

  • Based on clinical appearance
  • Confirmed by biopsy and histopathology
  • Important to rule out other conditions like leukoplakia or oral candidiasis

💊 Treatment:

  • No cure; treatment focuses on symptom relief:
    • Topical corticosteroids (e.g., fluocinonide, clobetasol)
    • Immune modulators (e.g., tacrolimus) for resistant cases
    • Good oral hygiene and avoiding irritants (spicy foods, tobacco)
  • Regular follow-up is essential due to small risk of malignant transformation

⚠️ Complications:

  • Rare risk of developing oral squamous cell carcinoma
  • Chronic discomfort impacting quality of life
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