Crohn’s disease

🦠 What Is Crohn’s Disease?

Crohn’s disease is a type of chronic inflammatory bowel disease (IBD) that causes inflammation of the digestive tract, most commonly affecting the small intestine and/or the beginning of the large intestine. However, it can affect any part of the gastrointestinal (GI) tract—from the mouth to the anus.

It is a lifelong condition that can flare up and go into remission.


🔍 Causes (Exact cause unknown, but may include):

  • Immune system dysfunction (abnormal response attacking the GI tract)
  • Genetic factors (family history increases risk)
  • Environmental factors (diet, stress, smoking)
  • Gut microbiome imbalance

⚠️ Symptoms:

  • Abdominal pain or cramping (often in the lower right side)
  • Chronic diarrhea (sometimes with blood or mucus)
  • Fatigue and weakness
  • Weight loss and poor appetite
  • Fever
  • Mouth sores
  • Joint pain or skin issues (extraintestinal symptoms)

🔁 Symptoms often come in flare-ups, followed by periods of remission.


🩺 Diagnosis:

  • Blood tests (anemia, inflammation markers)
  • Stool tests (to rule out infection)
  • Colonoscopy or endoscopy (to view inflammation and take biopsies)
  • Imaging (CT or MRI) to assess inflammation or complications

💊 Treatment:

There is no cure, but treatment helps manage symptoms and reduce flare-ups:

Medications:

  • Anti-inflammatory drugs (e.g., mesalamine)
  • Corticosteroids (for short-term inflammation control)
  • Immunosuppressants (e.g., azathioprine)
  • Biologics (e.g., infliximab, adalimumab)
  • Antibiotics (for complications like abscesses)

Other Treatments:

  • Nutritional therapy (special diets or supplements)
  • Surgery (if complications like strictures, fistulas, or severe inflammation occur)

🛡️ Lifestyle & Diet Tips:

  • Eat a low-residue or low-fiber diet during flares
  • Avoid trigger foods (e.g., dairy, fatty or spicy foods)
  • Stay hydrated
  • Don’t smoke
  • Manage stress

🧠 Complications:

  • Intestinal blockages or strictures
  • Fistulas (abnormal connections between organs)
  • Abscesses
  • Malnutrition
  • Colon cancer (long-term inflammation increases risk)
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